A novel approach to identifying C2 and C3 block vertebrae

Published Date: 01st January 2025

Publication Authors: Iyengar. KP

Abstract
Background: Congenital block vertebrae (BV) is a common condition resulting from segmentation disorders during embryonic development, leading to the fusion of adjacent vertebrae. BV at C2–C3 (cervical vertebrae 2nd–3rd) level is the most common segmentation anomaly. Labeling this correctly is the requirement for exact labeling of the spine. Diagnosing BV may not be challenging; however, differentiating BV from the long C2 can be tricky. Our study proposes a novel method of recognizing BV by measuring their height to aid in accurately distinguishing BV from normal vertebrae.

Methods: This retrospective study compared C2 vertebral heights between two groups: 50 patients with normal cervical spine magnetic resonance imaging (MRI) and 30 patients with congenital fusion at the C2–C3 levels. Using T2-weighted midsagittal MRI images, the height of the C2 vertebra was measured from the tip of the odontoid process to the posteroinferior part of the vertebra. Data analysis was performed using independent t-tests to evaluate the differences in measurements.

Results: The mean C2 vertebral height for the normal cervical spine group was 33.22 mm, while the congenital fusion group exhibited a significantly higher mean height of 45.59 mm. These findings were statistically significant, indicating that a C2 vertebral height exceeding 33 mm is atypical in normal individuals. Our proposed threshold measurement aids in distinguishing between single vertebrae and BV.

Conclusion: Our study provides a novel method for assessing C2 vertebral body height to aid in the numbering of cervical spine to enhance diagnostic accuracy in particular in patients with congenital anomalies.

 

Pellakuru, S.R.; Iyengar, K.P.; Et al. (2025). A novel approach to identifying C2 and C3 block vertebrae. Journal of Craniovertebral Junction and Spine. 16(1), pp.72-76. [Online]. Available at: https://dx.doi.org/10.4103/jcvjs.jcvjs_163_24 [Accessed 16 April 2025].

« Back